I have used obsidian and excallidraw for my note taking, especially excallidraw for math where I draw with my tablet. But since I started using emacs for programing I would like to move to org roam for school notes. However, I have not found a good alternative program for obsidians excallidraw plugin (I find gimp a bit to big for my purposes).
Never used it for notes, but yes inkscape. Inkscape is much more stable than it was in the past imho.