I’m an enby and soon to start HRT.

I just had a strange conversation with a friend is saying that estrogen is messing up their dopamine levels.

They said on the pills, they felt ok, but the dose was too low. And then switching to weekly injections, they get a high for 4 days and then they have like a depressive crash on the last 3 days.

It’s started a little bit of a spiral for me as god knows I’ve struggled with brain chemicals all my life. From drepression to anxiety and back and forth, but I’ve been doing much better the past year.

And so I’m kind of freaking out that estrogen will make me spin out.

Has anyone else had issues like this with the injections. I know its very subjective what people feel.