In short, a Cardassian was torturing Picard, and told him to admit (under torture) that there are 5 lights behind him, when there were obviously 4. Picard refused to break. The meme is playing that out with the “four vs five” word on the bottom left.
Good explanation of the TNG episode “Chain of Command”:
https://screenrant.com/star-trek-tng-there-are-four-lights-why-quote-important/
In short, a Cardassian was torturing Picard, and told him to admit (under torture) that there are 5 lights behind him, when there were obviously 4. Picard refused to break. The meme is playing that out with the “four vs five” word on the bottom left.
The raw part of that episode is that he did break in the end, but was rescued before he was forced to admit it.
They handled the truth of torture very well, which is that eventually everyone, even a hardnosed firebrand like Picard, will break.
Stewart really put those acting chops to work in that one.