nytimes.com
www.nytimes.com

Every household in the United States will be able to order four tests from Covidtests.gov between now and the end of the year. People can also get tests by calling 1-800-232-0233.

  • Badabinski@kbin.earth
    3·
    2 months ago

    It’s a shame that nobody has produced a molecular test cheaply enough for free distribution yet. The fact that you can get PCR quality tests entirely at home makes the antigen tests a non-option for me and mine. They’re too expensive to recommend to most people, however. The ones I’ve been using are $25 per test, and you also have to pay $50 for the reusable test reader. That’s way cheaper than they used to be (Lucira COVID tests were like $75 a pop, and the fact that the entire unit was single use was terrible from a waste perspective), but it’s still just not good enough.

    EDIT: lmao, Pfizer bought Lucira and is now selling combo COVID+flu tests with the same single-use tester. I wish they had converted to a reusable central unit with disposable tests like most other molecular COVID testers…

    EDIT: yikes, the Lucira combo tester might be giving false positive results for the flu. Dunno if this Amazon review is accurate, but it’s certainly concerning:

    Here is said Amazon review

    This is one of the first combo tests for flu and COVID-19. By training, I am a microbiologist and infectious disease epidemiologist. Thus, I ordered some of these new tests to see how well they worked and how easy they were. As additional background, I have run infectious disease laboratories and have designed diagnostic assays. Thus, having an at-home test is always a nice luxury.

    The instructions were easy to use. I will note that when you put the vial in the reader, do not push it all the way down, as that is when the test will actually start. So be sure to mix your swab in the buffer (purple liquid) for the appropriate time and then cap the viral and push down.

    I ran the first test (far left in the picture) and within 10 minutes it came up as positive for influenza B. Currently, in the US, in my age bracket, flu B makes up about 17% of diagnosed cases, so the biological rationale is that this could be real. However, I was asymptomatic and was only running the test to see how easy it was to run. I then retested on a rapid antigen test that included SARS-CoV-2, Flu A, Flu B, and RSV. These unfortunately are not available in the US but I had some left over from a trip to Europe. That was negative for all of those pathogens. Since these molecular tests have a lower limit of detection (meaning they can detect small amounts of viral nucleic acid compared to rapid antigen tests). However I did buy four of the Lucira tests, so I ran another one (far right in the photo). That came back negative for all of the pathogens.

    This is highly concerning. Given no diagnostic test is perfect, had I only had one test on hand and no way to corroborate the first test result I would have been isolating thinking that I had influenza B. When in actuality, it seems most likely that the first test was a false positive result. Looking at the Instructions for Use on the FDA website, it shows for Flu B, that in 364 PCR negative samples, 1 was positive on the Lucira test. So there is always a possibility that you test results may not be accurate. However, it was curious that this happened the first time I used this assay.

    I would personally avoid this product. I have been using many of the at-home tests for the past few years and have NEVER had a false positive. Thus, this has put much doubt into the results and the technology behind this product. This is the only molecular combo assay for SARS-CoV-2 and Flu on the market at this point, but others will be released shortly and I would interpret these results carefully. Really, I would love if they refunded me the cost of one test, but I won’t hold my breath there