Currently I’m using Joplin with Syncthing-backed file system synchronization. I’m pretty pleased with it, as I do like tagging- and Markdown-based systems.
I plan to upgrade to server-based synchronization, but before doing that, however, I wanted to see what other people are using.
Edit: So far I see a slight favor towards Joplin and Logseq, but I totally didn’t expect (and appreciate) getting so many different answers.
You can manually sync. Otherwise when you close it it syncs and you can also set the period for syncing.