I think the only officially confirmed thing is the pet rework, right? Everything else is up in the air. I’m still personally hoping for more railjack updates, for some UI work (an LFG tool or a better minimap/buff bar), maybe a way to favorite weapons or a better way to navigate the huge amount of gear we have.
In terms of cinematic quests and story I hope they focus a bit on smaller side stories instead of spending years on big new war / duviri content drops. Warframe has a big universe and they can do so much with it that is unrelated to Wally, the orokin or the tenno, but even those could use more smaller but more common updates IMHO.
I guess a big focus will be Soulframe but I’m not that invested in it (yet) so I hope it’s not the main thing they discuss.
I mostly want to see reworks of existing content. But I’ll set my hopes low to avoid the “never gonna happen” category: