CrimeDad@lemmy.crimedad.work to No Stupid Questions@lemmy.worldEnglish · edit-21 month agoCan harmless viruses be engineered to deliver vaccine payloads for different, actually harmful viruses?message-squaremessage-square17fedilinkarrow-up136arrow-down12file-text
arrow-up134arrow-down1message-squareCan harmless viruses be engineered to deliver vaccine payloads for different, actually harmful viruses?CrimeDad@lemmy.crimedad.work to No Stupid Questions@lemmy.worldEnglish · edit-21 month agomessage-square17fedilinkfile-text
minus-squaree0qdk@reddthat.comlinkfedilinkarrow-up25·1 month agoYes. There are virus vector vaccines already in existence: https://en.wikipedia.org/wiki/Viral_vector_vaccine For example, adenovirus vector vaccines were created for COVID-19: https://en.wikipedia.org/wiki/COVID-19_vaccine#Adenovirus_vector_vaccines Those are non-replicating though. Live attenuated vaccines also exist – which can replicate – but those work by using a weakened/modified version of the original harmful live virus the vaccine is intended to protect against: https://en.wikipedia.org/wiki/Attenuated_vaccine Oral polio vaccine is a well-known example.
Yes. There are virus vector vaccines already in existence: https://en.wikipedia.org/wiki/Viral_vector_vaccine
For example, adenovirus vector vaccines were created for COVID-19: https://en.wikipedia.org/wiki/COVID-19_vaccine#Adenovirus_vector_vaccines
Those are non-replicating though.
Live attenuated vaccines also exist – which can replicate – but those work by using a weakened/modified version of the original harmful live virus the vaccine is intended to protect against: https://en.wikipedia.org/wiki/Attenuated_vaccine
Oral polio vaccine is a well-known example.