Five people have been arrested and charged over the death of Matthew Perry, prosecutors said, including the actor’s personal assistant and two doctors.

The doctors supplied the Friends actor, who died at his Los Angeles home in October 2023, with a large amount of ketamine, the US attorney Martin Estrada said, and “took advantage of Mr Perry’s addiction issues to enrich themselves”.

Perry, 54, had publicly discussed his issues with addiction. He had been undergoing ketamine infusion therapy for anxiety and depression at the time of his death, the Los Angeles medical examiner said in an autopsy report last year, but the examiner found much higher levels of ketamine in the actor’s bloodstream than would be expected from the therapy alone.