For me it’s Corner Gas. I still think it’s pretty funny and there’s a decent amount of references to Canadian stuff but not enough to be off-putting. I feel like an American wouldn’t be confused watching it even if some of the references get a bit dated overtime.
I have only seen a bit of the animated version in waiting rooms.
I just started rewatching This Is Wonderland on Tubi.
Other than that, mostly ones that have already been mentioned plenty, but I’ll call out Due South and Murdoch Mysteries as big ones.