New research has found for the first time that PFAS “forever chemicals” accumulate in the testes, and the exposure probably affects children’s health.

The toxic chemicals can damage sperm during a sensitive developmental period, potentially leading to liver disease and higher cholesterol, especially in male offspring, the paper, which looked at the chemicals in mice, noted.

“We’ve always been concerned with maternal environmental health effects because women gestate the babies … but this research is really saying there is a paternal contribution to offspring health and development,” Pilsner added.

PFAS alters sperm DNA methylation, which is a process that turns genes on and off, Pilsner said. The methylation patterns can be inherited at fertilization and influence early-life development as well as offspring health later in life.