In the Dune universe, when a laser weapons hits a shield, both are destroyed in a nuclear explosion reaction.
So instead of building nuclear weapons, wouldn’t it be easier to tie a timer and a “parachute” to a laser gun and drop it from orbit onto your enemy’s city?
Hmm, I’ve taken a look and can only find references to the location being random so far. I was quite sure that I’ve also read that the magnitude could vary, but maybe I misremembered. I’ll dig a little further and see if I can find a reference.