Bro, people have been getting offended by South Park since it came out. Like let’s go back to Marvin the Starvin’ - it’s a pretty shitty and lazy depiction of Ethiopia, and the entire joke of the episode is “Sally Struthers is fat.” Is there anything in that episode that isn’t “slapstick, fart jokes and mild pop culture references”? The episode after that was Mr. Hankey the Christmas Poo! You better believe people were offended by talking shit on TV!

Sure, they used to be able to get away with showing Muhammad on the show (the concerns there are more ahem, macro aggressions). But I don’t see anything in modern South Park that really seems to indicate that they are pulling their punches (other than it’s just not as good, barring the games which are pretty great)

I’d also quibble with the characterization that they “take shots at everything” - Matt and Trey’s politics are obvious when you watch the show. You don’t find things in South Park offensive, because you likely share their ideology. I can say as a young trans person watching “Eek! A Penis!” for the first time was a pretty unpleasant experience.