Bought some vitamin D drops (liposomal) that say to take under the tongue. Now it’s surprisingly hard to actually do that. So how much am I missing out if it’s in the general mouth or on top of the tongue?

(I might try doing it in front of the mirror.)

  • Buffalox@lemmy.world
    91·
    9 months ago

    How does that work with vitamin D requiring fatty acids to be absorbed well?

    well absorbed in the small intestine. Absorption occurs by simple passive diffusion and by a mechanism that involves intestinal membrane carrier proteins [4]. The concurrent presence of fat in the gut enhances vitamin D absorption, but some vitamin D is absorbed even without dietary fat. Neither aging nor obesity alters vitamin D absorption from the gut.

    https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/

    • m-p{3}A
      11·
      9 months ago

      The vitamin D in drops is already encapsulated in fat to facilitate direct absorption (liposomal).

      • Buffalox@lemmy.world
        3·
        9 months ago

        I just never heard before, that you can uptake fat in your mouth. some water/salt solutions yes, but fat is new to me.
        Also I don’t see why it would be better than uptake through the small intestine, as you claim?

        • m-p{3}A
          2·
          9 months ago

          The sublingual (under the tongue) route of absorption is often considered preferable for certain substances because it allows for direct entry into the bloodstream, bypassing the digestive system. This can result in faster onset of action and higher bioavailability compared to absorption in the small intestine, where some substances may undergo partial degradation or be affected by first-pass metabolism in the liver before reaching systemic circulation.