That’s fine. 4 hours isn’t enough to really get into the meat of the game yet. If you feel like you’re kinda stumbling around a bit without quite knowing what the goal of the game is, that’s normal. The game is specifically designed to not give you any objectives, and a big part of making the game enjoyable is to not try to judge the game by regular game design conventions. There are no win conditions, no lose conditions, no objectives, and the game becomes much more enjoyable if you just play the game in the way that you think makes the most sense. You’ll just need to have a bit of faith that there is actually an end, you just never get told how to get to the end.

If you’re struggling with not crashing, then that’s a different issue altogether, and honestly my advice is to just use autopilot. Make sure to disable autopilot if you start to see that autopilot is going to crash you into the sun.

Outer Wilds. Any explanation that I give would be massive spoilers, but it captures a genre, aesthetic, and theme that, in my experience, has been virtually unused by any other game before and still remains extremely underutilized

Researchers spend $X to find out if microbes kill poison

No, that would implicitly admitthat pollution happens, which would never occur on Fox. Better version might be “see if dirt absorbs poison”

What’s New Pussycat on repeat, with an It’s Not Unusual thrown in sporadically

Reference: https://youtu.be/Tv1l1eUhN-E

Even just opening the link can leak info - I would avoid doing so entirely unless your device is sandboxed

That’s a bishop, not a pawn, but regardless, I don’t imagine that white has much of a chance

Here’s a fun game: describe your research/interest in a similar way that Fox/Republicans use to describe research. The more misleading it is from the actual research, the better.

I’ll start: watch how tired mice get when they get sick

(determine the mechanism of how microbial contact affects host circadian rhythms)

Contramuffin
AP Biology
Mrs. Setters
1 December 2024

          How cells respond to different doses of drugs 

Purpose: The purpose of this experiment is to see whether cells respond differently when exposed to different doses of the same drug. 

Hypothesis: The drugs will work the best at the highest dosage, but it won't work at the lowest dosage. 

Alternate hypothesis: All of the dosages work equally well. 

Materials:
* Cells
* 48-well plate
* Cell media 
* Recording device 
* Micropipettes
* Micropipette tips (a lot) 
* Serological pipers (a lot) 
* Serological piper pump
* Cell culture hood
* Drug (5 mg) 
* DMSO (5 mL) 
* PBS (5 ml) 
* Stimulus (500 uL) 
* PCR strip (2)

Procedure:
1. Using the cell culture hood, put cells and cell media into a 48-well plate
2. Put the plate into a recording device and start recording
3. Dilute drugs to the correct concentrations with DMSO
4. Put the drugs and the stimulant and the PBS into PCR strips for easier usage later
5. Stop the recording and put drugs into the plate 
6. Wait 30 minutes
7. Put stimulant or PBS into the plate 
8. Resume recording
9. After several days, stop the recording

Results: The cells died :'(

Conclusions: Science is hard

Herbal medicines are fine for minor things, but I wouldn’t use that for serious issues. Dosage is a big part of a medicine’s effectiveness, and a lot of the time, natural products have compounds that are too low in concentration to be reasonably effective. You’d need to extract and purify the compound, and at that point you’re right back to conventional medicine.

And that’s assuming that the herbs do contain the compound that you’re looking for, because unfortunately, people lie on the internet and I generally would not trust what random internet people say about what’s in herbal medicines

The fact that most of the weight localizes to the belly convinces me that there’s some sort of physiological reason behind this. Maybe your body is somehow reacting to the hormones from your wife, like a sort of pheromone? I get the want for privacy, but it seems like your case might be greatly beneficial for medical science.

Have you considered living elsewhere for a week or two to see what happens? Might be a simple (albeit potentially expensive) experiment

On the contrary, IME they significantly slowed down the early game, but they removed the early-mid-game dip right after you unlock fluids and oil processing

OK, so this is an interesting question. To start, I’m a circadian researcher, specifically focusing on how bacteria can influence our circadian clocks.

It is indeed correct that most animals utilize the sky (specifically, the ambient brightness) to determine the time. But the circadian clock is incredibly entrenched. It evolved ages ago, and so by extension, virtually every single animal inherited the same circadian clock (with some modifications). Animals as distinct as fruit flies, fish, and humans have similar circadian clocks. And the circadian clock is unbelievably important, more than people give it credit for. Night and day are incredibly different environments, and every single animal needs to be able to predict and accommodate for the cold that comes at night and the UV radiation that comes during the day. And there’s a plethora of other, subtle changes to the environment that we don’t fully understand yet. For instance (and probably a bit unsurprising in hindsight), the population of bacteria in the air changes at day versus at night. Soil bacteria, for some reason, act differently at day versus at night. Presumably plants (which are definitely circadian) are influencing the soil bacteria in some way through their roots, but it’s not entirely clear.

An interesting consequence of the importance of the circadian clock is that animals have evolved multiple, redundant ways of telling time. If you lock a person in a dark box for weeks to months (scientists have performed this experiment in the past), the circadian clock running within the person is still able to somewhat-accurately tell the time, and we can use experiments like this to tease apart how the circadian clock utilize different cues to figure out the right time. One of the more interesting cues (and the one that I research) is how our bodies use surrounding bacteria to tell the time. And it’s known that eating food affects the circadian clock. Food availability, of course, is pretty circadian, especially if you eat food that is circadian. If a mouse comes out at night, then there’s no point hunting for mice in the day. I’m not too knowledgeable about deep sea animals (I’m really more focused on mammals), but a quick literature search suggests that deep sea animals do have circadian clocks, inherited from the same ancient ancestors that we got ours from. The conclusions appear to be similar to what I’ve said above - namely, that even if there’s no sky, having a functional circadian clock is necessary simply because other things, such as food, are themselves circadian.

So my answer is, presumably, that deep sea animals can already accurately tell the time, presumably by keeping track of when they last ate

Let me introduce you to Goptjaam, probably the closest “language” that fits what you mean: https://youtu.be/ze5i_e_ryTk

You misunderstand. I’m willing - excited, even - to have restaurants that charge more upfront. I’m not willing to pay double the expected tip just because the restaurant hoped to hide additional costs in the bill and hoped that the payer wouldn’t see it. In case my original comment was not clear enough, that was what they tried doing. 15% gratuity tacked on in small letters at the end of the bill, and this charge was never mentioned at any point, and there was additional space to add tip (of course, with the recommended option being 15% after the 15% gratuity). The sum of the pre-included tip and the tip that I gave is equivalent to tip that I would have given had restaurant not tried this kind of shady bullshit. So I fail to see how I’ve done the workers of the restaurant any wrong.

I choose not to revisit that restaurant for their shady business practices, not because I was unwilling to pay a mandatory tip. Given the original post, I figured that that was clear that that was what I had meant. Clearly I was mistaken.

OOP jokes, but I’ve went to one or two restaurants that tried to do that in the past. I deducted the pre-included tip from the optional tip, and then never went to those restaurants again

The point, as I understand it, is that nuclear war can be technically won by nuking the enemy to smithereens and tanking their nukes as best as possible. The concern here is that because this would technically count as a victory, that it is a battle tactic that elitist assholes in the government have no doubt considered using.

Dating in South Korea is rough in general, more than other Asian countries. Apparently it’s devolved into a violent culture war. On one hand, it’s no wonder women are unwilling to date. On the other hand, that’s going to further fuel desperation and therefore extremist sentiment in men and further the downward spiral of the culture war.

I’m not saying that the male position is right here, but I genuinely do not see a possibility that the culture war stops spiraling

Wording is funky. To clarify:

The rain smell is due to a compound called geosmin. The bacteria that produces it is Streptomyces.

When I taught microbiology lab, I would grow a petri dish of Streptomyces during one particular class and have the students smell it

I genuinely don’t understand why people use it. It gives me massive motion sickness and so I figure out very quickly when games have it on by default