Identification of a leucine-mediated threshold effect governing macrophage mTOR signalling and cardiovascular risk - Nature Metabolism
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Zhang et al. use human studies and mechanistic work in mouse models to describe how leucine serves as the key amino acid derived from dietary protein to drive deleterious macrophage mTORC1 signalling and promote cardiovascular disease.
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The original was posted on /r/science by /u/mvea on 2024-02-20 11:55:24.

Original Title: A high-protein diet and elevation in the amino acid leucine may contribute to buildup of plaque in arteries. The study found a strong link between high protein consumption and atherosclerotic cardiovascular disease risk, indicating the possibility for diet advice and treatment measures.